Scientists on verge of curing diabeties...

o_psycnet · 12-15-2006, 07:49 PM

...candy sales to rise?

http://www.canada.com/nationalpost/n...b5d1bf&k=63970

Quote:

Originally Posted by National Post

In a discovery that has stunned even those behind it, scientists at a Toronto hospital say they have proof the body's nervous system helps trigger diabetes, opening the door to a potential near-cure of the disease that affects millions of Canadians.

Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas.

"I couldn't believe it," said Dr. Michael Salter, a pain expert at the Hospital for Sick Children and one of the scientists. "Mice with diabetes suddenly didn't have diabetes any more."

The researchers caution they have yet to confirm their findings in people, but say they expect results from human studies within a year or so. Any treatment that may emerge to help at least some patients would likely be years away from hitting the market.

o_tennovan · 12-15-2006, 08:05 PM

That's friggin amazing. Now on to the cure for AIDS and cancer(s)!

o_uber · 12-15-2006, 08:08 PM

Diabetes has been on the edge for a cure for quite a while, through various breakthroughs. Virtually all have been on mice and virtually all will take years to materialize.

o_tyrus · 12-15-2006, 08:41 PM

If I had a disease like Diabetes, I'd be willing to be a test subject if it meant that I "might not die".

o_uber · 12-15-2006, 08:45 PM

What is also meant you might die?

o_paft · 12-15-2006, 08:53 PM

A hopeful prospect.

o_tyrus · 12-15-2006, 08:54 PM

If the mice aren't dying and other test subjects of other species show the same results, I think it might be safe to assume a human wouldn't die. I'm basing that on nothing, but I think its an alright assumption.

No, I wouldn't be a test subject for a drug that has never ever been tested before. Thats just dumb. But, I'd be willing to put up with any side effect that the drug might have, as would tons of other people.

Take for example, kemotheropy. It has disastrous side effects, but millions of cancer patients seek this for what it 'can' do.

o_the russian · 12-15-2006, 09:07 PM

long term studies will be required if this is to pass the USDA, because of the nature of the drugs effect on the pancreas. From what this paragraph says it seems to work in the same manner that mad cow disease propagates through neuron connections. Lets not call it just yet.

I'm sorry, I'm a pessemist.

To show you the difference between human and other mammal physiology, you need not look further than chernobyl, where anyone within a certain area is eradiated, massive deaths from cancer and birth defects, while the animals are eradiated and are perfectly fine from birth, and actualy live longer and have no more human predation to worry about. Large hordes of radioactive bores and a big problem. As they cant be eaten or properly burried without contamination, nor burned without contamination.

There are also radioactive raindeer that survive where humans cant in the north eastern portions of russia where they tested nukes.

o_backstaber · 12-15-2006, 09:38 PM

Conclusion: We must find a radioactive chemical that does the opposite.

o_broodingdude · 12-15-2006, 10:01 PM

Don't cure AIDS. Then stupid people will breed again!

o_backstaber · 12-15-2006, 10:19 PM

DISCRIMINATION!

Circuitous · 12-15-2006, 11:06 PM

That's pretty cool, but The Russian's right (if overly verbose). Need to make sure they don't just revert to diabetic again.

Also since when can rats get diabetes?

o_the russian · 12-15-2006, 11:14 PM

Quote:

Originally Posted by Circuitous

That's pretty cool, but The Russian's right (if overly verbose). Need to make sure they don't just revert to diabetic again.

Also since when can rats get diabetes?

it has to be induced by drugs supressing or agitating the thyroid... depending on if you want to simulate type 1 or type 2 diabetes.

Circuitous · 12-15-2006, 11:18 PM

Well that's rude.

o_broodingdude · 12-15-2006, 11:51 PM

Quote:

Originally Posted by The Russian

simulate

Umm... yeah... ummm.... uhh... yeah.

o_binarylife · 12-16-2006, 02:51 PM

Actujaly animals can get diabetes the same way people can.

I've had two cats in my life time, and a dog which contracted diabetes.

Animals can contract the same illnesses that humans can. Even psycosis, while it's very rare.

Lost · 12-16-2006, 04:51 PM

The narcoleptic poodle was funny. Sad, but still funny.

o_dr zoidberg · 12-16-2006, 06:52 PM

I hardly think stuff that may have the side effect DEATH will ever be tried on humans.

Circuitous · 12-16-2006, 07:38 PM

Quote:

Originally Posted by Dr Zoidberg

I hardly think stuff that may have the side effect DEATH will ever be tried on humans.

Well, it has been.

A few drugs with "harmful, potentially fatal" side effects are readily available, even advertised on TV. Fun, eh?

o_paft · 12-17-2006, 11:00 AM

There was a documentary once I wanted to watch but i missed about human guinea pigs trialing drugs, there was a man who got black feet and hands it looked terrible.

DYING FOR DRUGS

A hard-hitting investigation into the global power of the world's most profitable business - the pharmaceutical industry. The programme reveals just how far drug companies are prepared to go to get their drugs approved and what they will do to make sure they get the prices they want.
In Africa the team sees how one of the world's biggest drug companies experimented on children without their parents' knowledge or consent. In Canada they reveal how a drug company attempted to silence a leading academic who had doubts about their drug. In South Korea cameras follow the attempts of desperately ill patients to make a leading drug company sell them the drugs they need to save their lives at an affordable price. And in Honduras the team uncovers the brutal consequences of drug companies' pricing policies.
This is a powerful film with alarming implications for everyone whose health depends on prescription medicines. If the power of these multi-nationals remains unchecked, many more people will soon be dying for drugs.

12-15-2006, 11:06 PM	#12
Circuitous Useless Retired FF Staff Join Date: Jun 2005 Class/Position: D Soldier, O Scout Gametype: AvD Posts Rated Helpful 9 Times	That's pretty cool, but The Russian's right (if overly verbose). Need to make sure they don't just revert to diabetic again. Also since when can rats get diabetes? __________________ Look at all those dead links.

12-15-2006, 11:18 PM	#14
Circuitous Useless Retired FF Staff Join Date: Jun 2005 Class/Position: D Soldier, O Scout Gametype: AvD Posts Rated Helpful 9 Times	Well that's rude. __________________ Look at all those dead links.

12-16-2006, 04:51 PM	#17
Lost Fear teh crowbar. Retired FF Staff Join Date: Jan 2005 Location: Oklahoma Gametype: CTF ftw, yeh Posts Rated Helpful 6 Times	The narcoleptic poodle was funny. Sad, but still funny. __________________ Do what you want cuz a pirate is free! You are a pirate!

12-15-2006, 08:05 PM	#2
o_tennovan Join Date: Jun 2005 Location: Texas Posts Rated Helpful 0 Times	That's friggin amazing. Now on to the cure for AIDS and cancer(s)!

12-15-2006, 08:08 PM	#3
o_uber Join Date: Jun 2005 Posts Rated Helpful 0 Times	Diabetes has been on the edge for a cure for quite a while, through various breakthroughs. Virtually all have been on mice and virtually all will take years to materialize.

12-15-2006, 08:41 PM	#4
o_tyrus Join Date: Dec 2005 Posts Rated Helpful 0 Times	If I had a disease like Diabetes, I'd be willing to be a test subject if it meant that I "might not die".

12-15-2006, 08:45 PM	#5
o_uber Join Date: Jun 2005 Posts Rated Helpful 0 Times	What is also meant you might die?

12-15-2006, 08:53 PM	#6
o_paft Join Date: Jan 2006 Location: United Kingdom Posts Rated Helpful 0 Times	A hopeful prospect.

12-15-2006, 08:54 PM	#7
o_tyrus Join Date: Dec 2005 Posts Rated Helpful 0 Times	If the mice aren't dying and other test subjects of other species show the same results, I think it might be safe to assume a human wouldn't die. I'm basing that on nothing, but I think its an alright assumption. No, I wouldn't be a test subject for a drug that has never ever been tested before. Thats just dumb. But, I'd be willing to put up with any side effect that the drug might have, as would tons of other people. Take for example, kemotheropy. It has disastrous side effects, but millions of cancer patients seek this for what it 'can' do.

12-15-2006, 09:07 PM	#8
o_the russian Join Date: Jul 2006 Location: Buffalo, NY Posts Rated Helpful 0 Times	long term studies will be required if this is to pass the USDA, because of the nature of the drugs effect on the pancreas. From what this paragraph says it seems to work in the same manner that mad cow disease propagates through neuron connections. Lets not call it just yet. I'm sorry, I'm a pessemist. To show you the difference between human and other mammal physiology, you need not look further than chernobyl, where anyone within a certain area is eradiated, massive deaths from cancer and birth defects, while the animals are eradiated and are perfectly fine from birth, and actualy live longer and have no more human predation to worry about. Large hordes of radioactive bores and a big problem. As they cant be eaten or properly burried without contamination, nor burned without contamination. There are also radioactive raindeer that survive where humans cant in the north eastern portions of russia where they tested nukes.

12-15-2006, 09:38 PM	#9
o_backstaber Join Date: Aug 2005 Location: New Jersey, USA! Posts Rated Helpful 0 Times	Conclusion: We must find a radioactive chemical that does the opposite.

12-15-2006, 10:01 PM	#10
o_broodingdude Join Date: Apr 2005 Location: Hawaii Posts Rated Helpful 0 Times	Don't cure AIDS. Then stupid people will breed again!

12-15-2006, 10:19 PM	#11
o_backstaber Join Date: Aug 2005 Location: New Jersey, USA! Posts Rated Helpful 0 Times	DISCRIMINATION!

12-16-2006, 02:51 PM	#16
o_binarylife Join Date: Jan 2005 Location: Pennsylvania Posts Rated Helpful 0 Times	Actujaly animals can get diabetes the same way people can. I've had two cats in my life time, and a dog which contracted diabetes. Animals can contract the same illnesses that humans can. Even psycosis, while it's very rare.

12-16-2006, 06:52 PM	#18
o_dr zoidberg Join Date: Apr 2005 Location: Sweden Posts Rated Helpful 0 Times	I hardly think stuff that may have the side effect DEATH will ever be tried on humans.

12-17-2006, 11:00 AM	#20
o_paft Join Date: Jan 2006 Location: United Kingdom Posts Rated Helpful 0 Times	There was a documentary once I wanted to watch but i missed about human guinea pigs trialing drugs, there was a man who got black feet and hands it looked terrible. DYING FOR DRUGS A hard-hitting investigation into the global power of the world's most profitable business - the pharmaceutical industry. The programme reveals just how far drug companies are prepared to go to get their drugs approved and what they will do to make sure they get the prices they want. In Africa the team sees how one of the world's biggest drug companies experimented on children without their parents' knowledge or consent. In Canada they reveal how a drug company attempted to silence a leading academic who had doubts about their drug. In South Korea cameras follow the attempts of desperately ill patients to make a leading drug company sell them the drugs they need to save their lives at an affordable price. And in Honduras the team uncovers the brutal consequences of drug companies' pricing policies. This is a powerful film with alarming implications for everyone whose health depends on prescription medicines. If the power of these multi-nationals remains unchecked, many more people will soon be dying for drugs.

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